Powered by Precision. Backed by Evidence.
ZBIOME™ was founded by scientists and healthcare professionals who saw a gap in effective probiotic solutions. We’ve bridged that gap with high-quality, research-based formulations designed to support gut health, immunity, and overall wellness.
Lactobacillus plantarum
What It Does
A powerhouse probiotic known for its ability to modulate the immune system, support the intestinal microflora, and enhance gut barrier function. Its unique ability to interact with the host’s immune responses makes it a promising agent in gut health and potential immunotherapy applications.
Why It Matters
- Helps restore balance in the gut microbiome.
- Enhances immune defense through cytokine modulation.
- Supports mucosal integrity and nutrient assimilation.
Tobias, J. et al. (2025). The benefits of Lactiplantibacillus plantarum: from immunomodulator to vaccine vector. Immunology Letters, 272, 106971. Read Study
Lactobacillus bulgaricus
What It Does
Lactobacillus bulgaricus is best known for strengthening the gut barrier. It promotes the expression of tight junction proteins like ZO-1 and Occludin, which are crucial for maintaining a strong and selective intestinal lining. Additionally, it reduces pro-inflammatory markers, creating a calmer gut environment.
Why It Matters
- Enhances epithelial cohesion to prevent “leaky gut.”
- Decreases inflammatory cytokines (IL-1β, IL-6, TNF-α).
- Increases anti-inflammatory IL-10 for balanced immune activity.
Ye, Y. et al. (2024). Lactobacillus alleviates intestinal epithelial barrier function through GPR43-mediated M2 macrophage polarization. Animal Diseases, 4(1). Read Study
Streptococcus thermophilus
What It Does
This strain plays multiple roles in gut and overall metabolic health. It promotes gastrointestinal comfort, improves intestinal adhesion, and even supports cholesterol management. Additionally, it produces bacteriocins and folate, offering antimicrobial and nutritional support.
Why It Matters
- Produces antioxidants and essential nutrients like folate.
- Helps regulate cholesterol.
- Enhances gut motility and nutrient absorption.
Kapse, N. et al. (2024). Unveiling the Probiotic Potential of Streptococcus thermophilus MCC0200: Insights from In Vitro Studies Corroborated with Genome Analysis. Microorganisms, 12(2). Read Study
Bifidobacterium longum
What It Does
One of the most prevalent species in healthy guts—especially in infants and elderly individuals—Bifidobacterium longum is associated with immune regulation, nutrient absorption, and microbial balance. It supports both the intestinal and systemic immune system.
Why It Matters
- Promotes healthy gut flora from infancy to old age.
- Enhances immune response and reduces gut inflammation.
- Contributes to energy metabolism and vitamin synthesis.
Longhi, G. et al. (2024). Highly conserved bifidobacteria in the human gut: Bifidobacterium longum subsp. longum as a potential modulator of elderly innate immunity. Beneficial Microbes. Read Study
Lactobacillus acidophilus
What It Does
This versatile strain enhances digestive function, reinforces the immune system, and helps maintain gut microbial balance. It supports lactose digestion, reduces gastrointestinal distress, and has anti-inflammatory effects throughout the gut.
Why It Matters
- Essential for daily digestive health.
Reduces bloating, gas, and irregularity. - Supports both innate and adaptive immunity.
Liu, Y. et al. (2024). Health-Promoting Effects of Lactobacillus Acidophilus and Its Technological Applications in Fermented Food Products and Beverages. Fermentation, 10(8), 380. Read Study
Prebiotics
What It Does
Prebiotics are non-digestible fibers that fuel probiotics. They create a nourishing environment in the gut that allows beneficial bacteria to flourish, leading to enhanced digestion, better immunity, and greater metabolic balance.
Why It Matters
- Promote the growth of beneficial bacteria.
- Contribute to gut pH balance.
- Assist in mineral absorption and energy production.
Singarayar, M. S. et al. (2024). Prebiotics: Comprehensive Analysis of Sources, Structural Characteristics and Mechanistic Roles in Disease Regulation. Microbial Pathogenesis. Read Study
Stronger Together: The Synergistic Effect
Combining digestive enzymes with probiotics enhances nutrient absorption, improves microbiota balance, and boosts immune defenses. Evidence supports this not only in humans but also in animal models like the Siberian sturgeon.
Why ZBIOME Stands Out
Gut Health Starts Here. Science-Backed, Cost-Smart Relief.
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| Strain Diversity | Patented strains tailored for gut health and immunity | Limited, generic combinations |
| Delivery Method | Delayed-release capsule for targeted delivery | Standard capsules, less effective |
| Gut Health Benefits | Supports digestion, nutrient absorption, and gut lining | Basic digestive support |
| Immune Support | Clinically proven strains for immune enhancement | Inconsistent or undocumented benefits |
| Added Nutrients | Includes prebiotics and essential vitamins | Often lacks complementary ingredients |
| Shelf Stability | Long shelf life via advanced encapsulation | Moderate, may require refrigeration |
| Artificial Additives | Free from artificial colors, flavors, and fillers | May contain fillers or synthetics |
How We Got Our Start
Born from a passion for gut health and a frustration with low-quality probiotics, ZBIOME™ is the product of scientific integrity and human-centered innovation.
What Makes Our Product Different
We don’t just toss strains into a capsule — we deliver synergistic, evidence-based formulations with optimized potency, purity, and delivery.
Why We Love What We Do
Because we know it works. Every bottle is a step toward feeling better, living better, and achieving balance from the inside out.
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