Problem: Struggle with digestive issues.

“This is the best probiotic and prebiotic supplement I’ve tried! ZBIOME Probiotic & Prebiotics with Digestive Enzymes has no side effects and delivers exactly as promised. I previously tried cheaper brands, but within two weeks, I knew I’d be returning to this one.”

Verified Icon Verified Customer
Product Image

ZBIOME Probiotic + Prebiotic + Digestive Enzymes

60 Billion CFU
60 Billion CFU
Delayed Release Capsules
Delayed Release Capsules
Vegan Friendly
Vegan Friendly

Support your gut and boost digestion with ZBIOME. Clinically researched strains + digestive enzymes for total balance. Say goodbye to bloating, constipation & digestive discomfort.

Clinically Effective
Clinically Effective
FDA Registered Facility
FDA Registered Facility
Third Party Lab Tested
Third Party Lab Tested
Vegan, Non-GMO, Filler-Free
Vegan, Non-GMO, Filler-Free
Money-Back Guarantee
Money-Back Guarantee

1. Select Your Bundle

2. Select Frequency

Free & fast shipping across the USA

Free shipping

39 -Day Guarantee

39 -Day Guarantee

Clinicians' Choice

60+ clinical studies & scientific papers highlighting the benefits of ZBIOME'S Probiotics ingredients.

ZBIOME is a clinically formulated probiotic designed to reset and optimize your gut microbiome over a 60-day journey. Each capsule delivers targeted strains that support digestive comfort, immune resilience, and mood balance*.

Consistency is key—daily use helps beneficial bacteria establish and thrive, allowing your digestive system to gradually rebalance and strengthen. Whether you're just starting your gut health transformation or maintaining long-term wellness, ZBIOME helps you feel better from the inside out.

  • Lactobacillus rhamnosus GG – Supports intestinal barrier and immune function
  • Bifidobacterium lactis HN019 – Promotes regularity and reduces bloating
  • Lactobacillus acidophilus LA-5 – Enhances nutrient absorption and gut comfort
  • Prebiotic Fiber (90% Inulin) – Fuels beneficial bacteria for sustained balance
  • Digestive Enzyme Complex: Helps break down proteins, fats, carbs, and fibers for better nutrient absorption

Delayed Release Vegetarian Capsule – Clean, allergen-free delivery systemFree from gluten, dairy, soy, and artificial additives.

Take 1 capsule daily, preferably with a meal. Use consistently daily to complete the full microbiome reset. For best results, stay hydrated and maintain a fiber-rich diet.

• SHIPPING: Orders are processed within 1–2 business days and shipped via USPS or other reliable carriers.
• RETURNS: If you're not satisfied, contact us within 30 days of delivery for a full refund—no questions asked.
• SUPPORT: Our team is here to help with any questions about your order or your gut health journey.

Your Gut Deserves the Best and it's

Your Gut Deserves the Best and it's free!

If you don't notice improvement in your gut health within 30-60 days, reach out to us and we'll make it right

View full details

ZBIOME 60-Day Gut Health Journey

Week 1–2: Foundation Setting

Initial digestive comfort as beneficial bacteria begin to establish in your gut microbiome.

Week 3-4: Early Changes

Improved regularity and reduced bloating as your gut flora starts to rebalance.

Week 5-6: Building Momentum

Enhanced energy levels and better nutrient absorption as your digestive system optimizes.

Week 7-8: Significant Progress

Noticeable improvements in overall gut comfort, mood stability, and immune function.

Day 57–60: Full Benefits

Complete microbiome transformation with sustained digestive wellness, enhanced immunity, and optimal gut-brain connection.

Left small image

2x More cellular benefits than other probiotics

Left small image
Right image
Icon

1000+ 5-Star Reviews

Trusted by Thousands:

Hear Why People Love ZBIOME

5.0

“Great probiotic!”

I’ve been taking this probiotic for a little while after switching from my last one and it’s been easy to add into my routine. I feel like my digestion has been more regular and overall my stomach feels calmer, so I'll be sticking with this brand going forward! The capsules are easy to take, and I like that it doesn’t upset my stomach!

Stephany

Verified

VERIFIED CUSTOMER

5.0

“This One Delivers!”

This probiotic actually delivers! Within days I had less bloating, better regularity, and more energy—without any stomach upset. No weird flavors, easy to take, clean ingredients, and it just works. Definitely keeping this in my routine. For the benefits and quality, the price seems on point.

Belouise G

Verified

VERIFIED CUSTOMER

5.0

“Life-Changing Gut Support”

The capsules are easy to take, and I love that it’s formulated with science-backed strains. It feels like a premium product without the premium price tag. I also respect the transparency behind the brand—no gimmicks, just clean ingredients and clear labeling. If you're looking for a probiotic that actually delivers, ZBIOME is worth it. I’ve already recommended it to friends and family, and I’ll definitely be reordering

Sameh

Verified

VERIFIED CUSTOMER

5.0

“ Great for Gut health”

Great product . And great value. It's really helping my IBS problems a lot! No problem with swallowing. I definitely will be buying again.

Sharon M.

Verified

VERIFIED CUSTOMER

5.0

“5.0 out of 5 stars Game-Changer for Gut Health!”

I’ve tried several probiotics, but this one is hands down the best! Within just a few days, I noticed a huge difference—less bloating, more regularity, and zero discomfort. The 60 Billion CFU formula with prebiotics and butyrate really works. My digestion feels balanced, and I feel lighter and more energized throughout the day. No weird aftertaste, and it’s gentle on my stomach. Highly recommend for anyone dealing with gas, bloating, or irregularity. This is now a staple in my daily routine!

Jessinda Dahlin

Verified

VERIFIED CUSTOMER

5.0

“Haven’t been sick in months!”

The capsules are easy to take, and I love that it’s formulated with science-backed strains. It feels like a premium product without the premium price tag. I also respect the transparency behind the brand—no gimmicks, just clean ingredients and clear labeling. If you're looking for a probiotic that actually delivers, ZBIOME is worth it. I’ve already recommended it to friends and family, and I’ll definitely be reordering

Sameh

Verified

VERIFIED CUSTOMER

Unlock Your Wellness: Clinically-Backed Ingredients for Optimal Gut and Skin Health

Skin-Gut Axis Support

Skin-Gut Axis Support

Promotes clearer, healthier skin by addressing gut inflammation that often manifests as acne, eczema, and other skin conditions through the gut-skin connection.

Immune System Strengthening

Immune System Strengthening

Bolsters immune defense as 70% of your immune system resides in the gut, helping your body better fight off harmful pathogens and maintain overall wellness.

Brain-Gut Communication

Brain-Gut Communication

Enhances mood and mental clarity by supporting the gut-brain axis, where beneficial bacteria produce neurotransmitters like serotonin that regulate stress and emotional well-being.

Digestive Foundation

Digestive Foundation

Restores optimal digestive function by replenishing beneficial bacteria, improving nutrient absorption and reducing bloating, gas, and irregularity.

Wellness Image

Real Stories, Real Results:
See How ZBIOME Changes Lives

Reduced occasional bloating and gas. Gut microflora begins to rebalance with beneficial strains.

Science-backed gut health that fits your budget. Clinically formulated probiotics + enzymes for real digestive relief. Feel the difference in days, not months.

Trusted by thousands. Loved for results. Premium ingredients. No bloated pricing.

Your microbiome deserves better. Potent, clean, and crafted for everyday gut resilience.

Digestive support that goes beyond probiotics. Enzyme-enhanced formula for total gut harmony.

From bloated to balanced—naturally. ZBIOME’s targeted strains work where it counts.

Smart gut care without the markup. Transparent pricing. No fillers. Just results.

The probiotic upgrade your body’s been waiting for. Formulated for absorption, impact, and long-term wellness.

"Premium probiotics without the premium price. High-potency formula with digestive enzymes for maximum gut support."

Why ZBiome? Because Your Gut Deserves the Best

ZBIOME includes 10 powerful probiotic strains, each selected for specific gut.

Clinically Effective

Clinically Effective

ZBIOME includes 10 powerful probiotic strains, each selected for specific gut.

Third-Party Lab Verified

Third-Party Lab Verified

To confirm potency, purity, and safety—free from contaminants, banned substances, or unwanted additives.

Full Label Transparency

Full Label Transparency

No proprietary blends, no surprises—just full transparency you can trust for honest, science-backed supplementation.

Made in FDA-Registered U.S. Facilities

Made in FDA-Registered U.S. Facilities

In FDA-inspected, cGMP-compliant facilities using globally sourced, high-quality ingredients that meet strict purity and safety standards.

Money-Back Guarantee

Money-Back Guarantee

We’ll refund your purchase—no forms, no returns, no hassle. Experience ZBIOME risk-free and feel confident in your choice.

ZBiome Image

"Since I started this a month ago I have felt great, energetic, and sleeping better."

Verified Verified Buyer

"Since I started this a month ago I have felt great, energetic, and sleeping better."

Verified Verified Buyer

The Power Packed Inside Every ZBIOME Capsule

Our capsules contain a carefully selected blend of probiotics, prebiotics, and digestive enzymes designed to support gut health, improve digestion, and boost immunity.

Multi Strain 60 Billion CFU Probiotic Complex‡ (154mg†)

Multi Strain 60 Billion CFU Probiotic Complex‡ (154mg†)

Lactobacillus plantarum, Lactobacillus bulgaricus, Streptococcus thermophilus, Bifidobacterium longum, Lactobacillus acidophilus, Lactobacillus casei, Lactobacillus salivarius, Lactobacillus rhamnosus, Bifidobacterium lactis, Bifidobacterium bifidum
Prebiotic Complex◊ (150mg†)

Prebiotic Complex◊ (150mg†)

Blue Agave Heart◊ (Agave tequilana) (90% Inulin), Jerusalem Artichoke Root◊ (Helianthus tuberosus)
Digestive Enzyme Complex(200mg†)

Digestive Enzyme Complex(200mg†)

Protease (500 HUT), Papain (400 TU), Amylase (200 SKB), Lipase (150 FIP), Cellulase (100 CU), Lactase (60 ALU), Maltase (30 DP), Glucoamylase (2 AG), Bromelain (2 GDU)
Clinically Effective
Third-Party Lab Verified
Full Label Transparency
Vegan, Non-GMO, Filler-Free
Made in FDA-Registered U.S. Facilities
Money-Back Guarantee
Clinically Effective
Third-Party Lab Verified
Full Label Transparency
Vegan, Non-GMO, Filler-Free
Made in FDA-Registered U.S. Facilities
Money-Back Guarantee
Clinically Effective
Third-Party Lab Verified
Full Label Transparency
Vegan, Non-GMO, Filler-Free
Made in FDA-Registered U.S. Facilities
Money-Back Guarantee

Experts Agree Why ZBIOME is the Smart Choice for Gut Health

img_alt
image
image

“Hi, I'm Andrew mastro, physician assistant in dermatology with nearly a decade treating acne, psoriasis, and inflammatory skin conditions. Today, I want to share something that's revolutionizing how we approach skin Health. The gut skin axis is a fascinating area of research. Our intestible microbiome influences systemic inflammation through immune modulation. Metabolite production, which can affect skin barrier function and inflammatory responses.”

Andrew Mastro, PA-C
physician assistant in dermatology

“Consistency is everything when it comes to gut health. Your microbiome is a complex ecosystem—it doesn’t transform overnight. That’s why daily use of a high-quality probiotic is key. ZBIOME delivers exactly that: 10 clinically studied strains, 60 billion CFUs, plus digestive enzymes and plant-based prebiotics—all in one capsule. It’s a complete formula designed to reset your gut, support digestion, and fuel long-term wellness. Stick with it daily, and your microbiome will thank you.”

Dr. Moe, PharmD
Clinical Pharmacist

Why ZBIOME Stands Out: Compare the Difference Yourself

Product Features

Competitive price

Naturally great taste

Whole body wellness support

3rd party tested for quality

Advanced protective delivery

No synthetic fillers, toxins, or additives

Gluten-free, dairy-free, sugar-free

3-in-1 action (Prebiotic + Digestive Enzymes)

$27/mo

Leading standard capsules

$60/mo

Anti-caking agents

Unclear

Leading liquid probiotic

$50/mo

Preservatives, colorings

Unclear

Leading powder probiotic

$60/mo

Anti-caking agents

Unclear

Still Wondering? Here’s Everything You Need to Know

Whether you’re curious about our ingredients, shipping, or what works best for your Gut — find quick answers to the things people ask most.

Probiotics are beneficial bacteria that help balance your gut microbiome, supporting digestion, immunity, and mood.

Prebiotics are plant-based fibers that feed those good bacteria, helping them thrive and multiply. ZBIOME combines both for a synergistic effect that promotes long-term gut health.

ZBIOME™ delivers a targeted blend of probiotics, prebiotics, and digestive enzymes that work together to:

  • Improve regularity and reduce bloating
  • Enhance nutrient absorption

Support the breakdown of proteins, fats, and carbohydrates This triple-action formula helps your digestive system function more efficiently—day after day.

ZBIOME™ is formulated to be gentle and effective for most adults. It’s vegan, gluten-free, non-GMO, and free from common allergens. However, if you’re pregnant, nursing, or have a medical condition, we recommend consulting your healthcare provider before starting any new supplement.

Many users begin to notice improvements in digestion and energy within 2–4 weeks. For full microbiome transformation, we recommend consistent daily use for 60 days. Gut health is a journey—consistency is key.

Yes. ZBIOME™ is safe to take alongside most vitamins and supplements. If you're using prescription medications or other probiotics, consult your healthcare provider to ensure compatibility.

Store ZBIOME in a cool, dry place away from direct sunlight. No refrigeration is required. Keep the bottle tightly closed to preserve potency.

Rating Stars
Rating Stars

1000+ 5-Star Reviews

Love ZBIOME?

Earn With Us.

Join our growing community of gut health advocates. Access to commissions, samples, and exclusive content.

Apply Now
Main Product Image

Customer Reviews

Based on 171 reviews
99%
(169)
0%
(0)
1%
(1)
1%
(1)
0%
(0)
B
Bridget C.
It works as described

So far so good. Already placed my second order via subscription. Only supplement that worked for bloating.

N
Nancy
Zbiome

It's only been a week still have bloating. Haven't seen any changes yet

J
James E.
Great product

Was taking Seed and Align before switching to ZBIOME. It works well for me. I noticed that the first 2 weeks were adjustment period but now more regular and helped relieve bloating.

D
Denise T.
This has been a game changer!

I have struggled with gut issues for quite sometime.

This product has really helped in just a short two weeks.

I will definitely be ordering again.

C
Christopher

So far so good