Zbiome prebiotics for gut health, 60 Billion CFU
Zbiome probiotics for digestive support, Immune support, and good bacteria
Supplement facts for Zbiome prebiotic digestive enzymes.
60 clinical studies and scientific papers for Zbiome gut support prebiotics - grey background
Clinically Effective

We don’t guess, we dose exactly what the science supports.

ZBIOME includes 10 powerful probiotic strains, each selected for specific gut and immune benefits, backed by 60+ published studies.

Third-Party Lab Verified

ZBIOME is independently lab-tested in ISO-accredited facilities:

To confirm potency, purity, and safety—free from contaminants, banned substances, or unwanted additives.

Full Label Transparency

We clearly list every ingredient and dosage.

No proprietary blends, no surprises—just full transparency you can trust for honest, science-backed supplementation.

Vegan, Non-GMO, Filler-Free

Our formula is clean:

100% vegan, non-GMO, and free from gluten, soy, dairy, fillers, artificial colors, and preservatives. Just what your gut needs—nothing more.

Made in FDA-Registered U.S. Facilities

Manufactured in the USA:

In FDA-inspected, cGMP-compliant facilities using globally sourced, high-quality ingredients that meet strict purity and safety standards.

Money-Back Guarantee

If you're not feeling the difference

We’ll refund your purchase—no forms, no returns, no hassle. Experience ZBIOME risk-free and feel confident in your choice.

ZBIOME Probiotic + Prebiotic + Digestive Enzymes

ZBIOME Probiotic + Prebiotic + Digestive Enzymes

  • 60 BillionCFU
  • 30 Capsules
  • Vegan Friendly

Support your gut and boost digestion with ZBIOME. Clinically researched strains + digestive enzymes for total balance. Delayed-release vegan capsules for targeted delivery. Say goodbye to bloating, constipation & digestive discomfort.

Free & fast shipping across the USA

View full details
Clinically Effective

We don’t guess, we dose exactly what the science supports.

ZBIOME includes 10 powerful probiotic strains, each selected for specific gut and immune benefits, backed by 60+ published studies.

Third-Party Lab Verified

ZBIOME is independently lab-tested in ISO-accredited facilities:

To confirm potency, purity, and safety—free from contaminants, banned substances, or unwanted additives.

Full Label Transparency

We clearly list every ingredient and dosage.

No proprietary blends, no surprises—just full transparency you can trust for honest, science-backed supplementation.

Vegan, Non-GMO, Filler-Free

Our formula is clean:

100% vegan, non-GMO, and free from gluten, soy, dairy, fillers, artificial colors, and preservatives. Just what your gut needs—nothing more.

Made in FDA-Registered U.S. Facilities

Manufactured in the USA:

In FDA-inspected, cGMP-compliant facilities using globally sourced, high-quality ingredients that meet strict purity and safety standards.

Money-Back Guarantee

If you're not feeling the difference

We’ll refund your purchase—no forms, no returns, no hassle. Experience ZBIOME risk-free and feel confident in your choice.

How ZBIOME Works Over Time

Here's what you may notice with consistent supplementation:

Day 1–2

Digestive enzymes begin breaking down nutrients for easier absorption. Some users notice lighter digestion after meals.*

Day 7

Reduced occasional bloating and gas. Gut microflora begins to rebalance with beneficial strains.*

Day 14

Improved stool consistency and regularity. Enhanced energy and less sluggishness tied to digestion.*

Day 30

Strengthened gut lining and microbiome diversity. Noticeable improvement in digestion, mood, and immune response.*

Customer Reviews

Based on 57 reviews
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R
Ray S.
Finally Found the Gut Support I Needed!

I’ve tried a number of probiotics and prebiotic supplements over the years, but ZBiome truly stands out. Within just a couple of weeks of using it consistently, I noticed a significant difference in my digestion and overall energy. No more bloating after meals, and my gut feels balanced.

What I love most is that it’s both a probiotic & a prebiotic, so you’re getting complete support in one convenient daily dose. Plus, I really appreciate that ZBiome is backed by science and formulated with strains designed to actually survive the journey through the digestive system (a problem I’ve had with other brands).

The packaging is clean, the ingredients are clearly listed, and it’s easy to incorporate into my daily routine. I feel better knowing I’m supporting my gut health naturally.

Highly recommend if you’re looking for a trustworthy, effective guy health supplement!

B
Betty H.
Professional quality, consumer price

As a healthcare professional, I'm particular about the supplements I take. ZBIOME impressed me with its comprehensive formula that rivals professional-grade products I've recommended to patients. The results have been excellent for my own digestive issues, and the price makes it accessible for everyone.

D
Donald F.
Regularity without harsh laxatives

I struggled with constipation for years and relied on laxatives too often. ZBIOME has helped establish a natural, regular pattern without harsh stimulants. The combination of probiotics with digestive enzymes seems to be the perfect solution for my system.

W
William T.
Gentle yet effective

Many probiotics I've tried caused initial discomfort as my body adjusted. ZBIOME was different - no adjustment period, just gradual improvement in my digestion. It's potent but gentle, and the price is right. Will be my go-to probiotic from now on.

O
Olivia G.
No more acid reflux

I've suffered from acid reflux for years and tried everything. Within two weeks of taking ZBIOME, my symptoms improved dramatically. I can now enjoy foods I had to avoid before. The combination of probiotics with digestive enzymes seems to be the perfect solution for me.

What People Are Saying

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Premium probiotics without the premium price. High-potency formula with digestive enzymes for maximum gut support.

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Support your gut, strengthen your immune system—ZBIOME delivers premium probiotics for total wellness.

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Consistency is key—add ZBIOME to your daily routine and enjoy effortless regularity.

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Science meets gut health. A research-backed probiotic designed to deliver real results.

Ingredients

Take 1 capsule daily with water, ideally before a meal.

Supplement Facts

Amount Per Serving %DV

Multi Strain 60 Billion CFU Probiotic Complex‡ 154mg

Lactobacillus plantarum, Lactobacillus bulgaricus, Streptococcus thermophilus, Bifidobacterium longum, Lactobacillus acidophilus, Lactobacillus casei, Lactobacillus salivarius, Lactobacillus rhamnosus, Bifidobacterium lactis, Bifidobacterium bifidum

Prebiotic Complex◊ 150mg

Blue Agave Heart◊ (Agave tequilana) (90% Inulin), Jerusalem Artichoke Root◊ (Helianthus tuberosus)

Digestive Enzyme Complex 200mg

Protease (500 HUT), Papain (400 TU), Amylase (200 SKB), Lipase (150 FIP), Cellulase (100 CU), Lactase (60 ALU), Maltase (30 DP), Glucoamylase (2 AG), Bromelain (2 GDU)

  • ‡Colony Forming Units at time of manufacture.
  • † Daily Value (DV) not established.

Lactobacillus plantarum

Offers health benefits by altering intestinal microflora and modulating immune responses, thereby enhancing overall human health. Its probiotic properties contribute to improved gut health and may also serve as a vaccine vector for targeted immunotherapy.

Tobias, J., Heinl, S., Dendinovic, K., Ramić, A., Schmid, A., Daniel, C., & Wiedermann, U. (2025). The benefits of Lactiplantibacillus plantarum: from immunomodulator to vaccine vector. Immunology Letters, 272, 106971. https://doi.org/10.1016/j.imlet.2025.106971 

Lactobacillus bulgaricus

Improves intestinal barrier integrity by increasing the expression of tight junction proteins such as ZO-1 and Occludin, which are crucial for maintaining epithelial cell cohesion(Ye et al., 2024). It also reduces inflammatory cytokines (IL-1B, IL-6, TNF-a) and promotes anti-inflammatory cytokines (IL-10), thereby mitigating intestinal inflammation(Ye et al., 2024)(Rastogi & Singh, 2022).

Ye, Y., Zhang, Y., Song, M., Fan, J., Feng, S., Li, J., Wu, Z., Zuo, B., Tao, S., & Liu, X. (2024). Lactobacillus alleviates intestinal epithelial barrier function through GPR43-mediated M2 macrophage polarization. Animal Diseases, 4(1). https://doi.org/10.1186/544149-024-00125-v

Streptococcus thermophilus

May offer health benefits such as improved gastrointestinal transit, intestinal adhesion, cholesterol reduction, production of beneficial compounds like folate and bacteriocins, and antioxidant enzyme release, all contributing to its potential as a probiotic.

Kapse, N., Pisu, V., Dhakephalkar, T., Margale, P., Shetty, D., Wagh, S., Dagar, S. S., & Dhakephalkar, P. K. (2024). Unveiling the Probiotic Potential of Streptococcus thermophilus MCC0200: Insights from In Vitro Studies Corroborated with Genome Analysis. Microorganisms. https://doi.org/10.3390/microorganisms12020347

Bifidobacterium longum

Plays a crucial role in the human gut microbiome, significantly influencing overall health through various mechanisms. This species is prevalent in the intestines of healthy individuals, particularly in infants and the elderly, and is recognized for its probiotic properties, including immunomodulation, nutrient absorption, and metabolic regulation. The following sections elaborate on its key roles and health implications.

Longhi, G., Lugli, G. A., Bianchi, M. G., Rizzo, S. M., Tarracchini, C., Mancabelli, L., Vergnà, L. M., Alessandri, G., Fontana, F., Taurino, G., Chiu, M., Milani, C., van Sinderen, D., Bussolati, O., Ventura, M., & Turroni, F. (2024). Highly conserved bifidobacteria in the human gut: Bifidobacterium longum subsp. longum as a potential modulator of elderly innate immunity. Beneficial Microbes, 1–18. https://doi.org/10.1863/18762891-bja00013

Lactobacillus acidophilus

Plays a crucial role in maintaining gut health and modulating the immune system through various mechanisms. This probiotic bacterium not only enhances digestive wellness but also influences immune responses, making it a vital component of the human microbiota.

Liu, Y., Nawazish, H., Farid, M. S., Qadoos, K. A., Habiba, U. E., Muzamil, M., Tanweer, M., Sienkiewicz, M., Lichota, A., & Łopusiewicz, Ł. (2024). Health-Promoting Effects of Lactobacillus Acidophilus and Its Technological Applications in Fermented Food Products and Beverages. Fermentation, 10(8), 380. https://doi.org/10.3390/fermentation10080380

Prebiotics

Prebiotics play a vital role in enhancing human health by modulating the gut microbiome, which is crucial for various physiological functions. These non-digestible carbohydrates selectively stimulate the growth of beneficial gut bacteria, leading to numerous health benefits. The following sections outline the specific health benefits of prebiotics.


Singarayar, M. S., Chandrasekaran, A., Balasundaram, D., Veerasamy, V. S., Neethirajan, V., & Thilagar, S. (2024). Prebiotics: Comprehensive Analysis of Sources, Structural Characteristics and Mechanistic Roles in Disease Regulation. Microbial Pathogenesis, 107071. https://doi.org/10.1016/j.micpath.2024.107071

See How
We Compare

Gut Health Starts Here. Science-Backed, Cost-Smart Relief.

ZBIOME Probiotic & Prebiotics with Digestive Enzymes

A great gut health Supplement

From $27

10 clinically studied strains

Delayed-release capsules

9 Enzyme-blend

150 mg of probiotics

Shelf-stable

No fillers or colors

Other brand’s supplement

Generic Health Suplement

Over $40

2–3 generic strains

Regular capsules

None

Often missing

Not always

Often fillers

Further Questions?

What makes ZBIOME different from other probiotics?

ZBIOME is formulated with clinically studied strains designed to support gut health, digestion, and overall wellness. Our unique blend ensures optimal absorption and effectiveness, helping you feel your best every day.

How should I take ZBIOME for best results?

For maximum benefits, take one capsule daily with water, preferably with a meal. Consistency is key—regular use helps maintain a balanced gut microbiome.

Is ZBIOME suitable for all dietary preferences?

Yes! ZBIOME is vegan, gluten-free, and non-GMO, making it a great choice for various dietary needs. We prioritize clean ingredients to ensure quality and effectiveness.

How long does it take to see results with ZBIOME?

While individual experiences vary, many users notice improvements in digestion and overall well-being within 2-4 weeks of consistent use. Long-term benefits continue with regular supplementation.

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