






We don’t guess, we dose exactly what the science supports.
ZBIOME includes 10 powerful probiotic strains, each selected for specific gut and immune benefits, backed by 60+ published studies.



ZBIOME is independently lab-tested in ISO-accredited facilities:
To confirm potency, purity, and safety—free from contaminants, banned substances, or unwanted additives.



We clearly list every ingredient and dosage.
No proprietary blends, no surprises—just full transparency you can trust for honest, science-backed supplementation.



Our formula is clean:
100% vegan, non-GMO, and free from gluten, soy, dairy, fillers, artificial colors, and preservatives. Just what your gut needs—nothing more.



Manufactured in the USA:
In FDA-inspected, cGMP-compliant facilities using globally sourced, high-quality ingredients that meet strict purity and safety standards.



If you're not feeling the difference
We’ll refund your purchase—no forms, no returns, no hassle. Experience ZBIOME risk-free and feel confident in your choice.



We don’t guess, we dose exactly what the science supports.
ZBIOME includes 10 powerful probiotic strains, each selected for specific gut and immune benefits, backed by 60+ published studies.



ZBIOME is independently lab-tested in ISO-accredited facilities:
To confirm potency, purity, and safety—free from contaminants, banned substances, or unwanted additives.



We clearly list every ingredient and dosage.
No proprietary blends, no surprises—just full transparency you can trust for honest, science-backed supplementation.



Our formula is clean:
100% vegan, non-GMO, and free from gluten, soy, dairy, fillers, artificial colors, and preservatives. Just what your gut needs—nothing more.



Manufactured in the USA:
In FDA-inspected, cGMP-compliant facilities using globally sourced, high-quality ingredients that meet strict purity and safety standards.



If you're not feeling the difference
We’ll refund your purchase—no forms, no returns, no hassle. Experience ZBIOME risk-free and feel confident in your choice.




What People Are Saying
Supplement Facts
Multi Strain 60 Billion CFU Probiotic Complex‡ 154mg
Prebiotic Complex◊ 150mg
Digestive Enzyme Complex 200mg
Protease (500 HUT), Papain (400 TU), Amylase (200 SKB), Lipase (150 FIP), Cellulase (100 CU), Lactase (60 ALU), Maltase (30 DP), Glucoamylase (2 AG), Bromelain (2 GDU)
- ‡Colony Forming Units at time of manufacture.
- † Daily Value (DV) not established.
Lactobacillus plantarum
Offers health benefits by altering intestinal microflora and modulating immune responses, thereby enhancing overall human health. Its probiotic properties contribute to improved gut health and may also serve as a vaccine vector for targeted immunotherapy.
Tobias, J., Heinl, S., Dendinovic, K., Ramić, A., Schmid, A., Daniel, C., & Wiedermann, U. (2025). The benefits of Lactiplantibacillus plantarum: from immunomodulator to vaccine vector. Immunology Letters, 272, 106971. https://doi.org/10.1016/j.imlet.2025.106971
Lactobacillus bulgaricus
Improves intestinal barrier integrity by increasing the expression of tight junction proteins such as ZO-1 and Occludin, which are crucial for maintaining epithelial cell cohesion(Ye et al., 2024). It also reduces inflammatory cytokines (IL-1B, IL-6, TNF-a) and promotes anti-inflammatory cytokines (IL-10), thereby mitigating intestinal inflammation(Ye et al., 2024)(Rastogi & Singh, 2022).
Ye, Y., Zhang, Y., Song, M., Fan, J., Feng, S., Li, J., Wu, Z., Zuo, B., Tao, S., & Liu, X. (2024). Lactobacillus alleviates intestinal epithelial barrier function through GPR43-mediated M2 macrophage polarization. Animal Diseases, 4(1). https://doi.org/10.1186/544149-024-00125-v
Streptococcus thermophilus
May offer health benefits such as improved gastrointestinal transit, intestinal adhesion, cholesterol reduction, production of beneficial compounds like folate and bacteriocins, and antioxidant enzyme release, all contributing to its potential as a probiotic.
Kapse, N., Pisu, V., Dhakephalkar, T., Margale, P., Shetty, D., Wagh, S., Dagar, S. S., & Dhakephalkar, P. K. (2024). Unveiling the Probiotic Potential of Streptococcus thermophilus MCC0200: Insights from In Vitro Studies Corroborated with Genome Analysis. Microorganisms. https://doi.org/10.3390/microorganisms12020347
Bifidobacterium longum
Plays a crucial role in the human gut microbiome, significantly influencing overall health through various mechanisms. This species is prevalent in the intestines of healthy individuals, particularly in infants and the elderly, and is recognized for its probiotic properties, including immunomodulation, nutrient absorption, and metabolic regulation. The following sections elaborate on its key roles and health implications.
Longhi, G., Lugli, G. A., Bianchi, M. G., Rizzo, S. M., Tarracchini, C., Mancabelli, L., Vergnà, L. M., Alessandri, G., Fontana, F., Taurino, G., Chiu, M., Milani, C., van Sinderen, D., Bussolati, O., Ventura, M., & Turroni, F. (2024). Highly conserved bifidobacteria in the human gut: Bifidobacterium longum subsp. longum as a potential modulator of elderly innate immunity. Beneficial Microbes, 1–18. https://doi.org/10.1863/18762891-bja00013
Lactobacillus acidophilus
Plays a crucial role in maintaining gut health and modulating the immune system through various mechanisms. This probiotic bacterium not only enhances digestive wellness but also influences immune responses, making it a vital component of the human microbiota.
Liu, Y., Nawazish, H., Farid, M. S., Qadoos, K. A., Habiba, U. E., Muzamil, M., Tanweer, M., Sienkiewicz, M., Lichota, A., & Łopusiewicz, Ł. (2024). Health-Promoting Effects of Lactobacillus Acidophilus and Its Technological Applications in Fermented Food Products and Beverages. Fermentation, 10(8), 380. https://doi.org/10.3390/fermentation10080380
Prebiotics
Prebiotics play a vital role in enhancing human health by modulating the gut microbiome, which is crucial for various physiological functions. These non-digestible carbohydrates selectively stimulate the growth of beneficial gut bacteria, leading to numerous health benefits. The following sections outline the specific health benefits of prebiotics.
Singarayar, M. S., Chandrasekaran, A., Balasundaram, D., Veerasamy, V. S., Neethirajan, V., & Thilagar, S. (2024). Prebiotics: Comprehensive Analysis of Sources, Structural Characteristics and Mechanistic Roles in Disease Regulation. Microbial Pathogenesis, 107071. https://doi.org/10.1016/j.micpath.2024.107071
See How
We Compare
Gut Health Starts Here. Science-Backed, Cost-Smart Relief.


ZBIOME Probiotic & Prebiotics with Digestive Enzymes
A great gut health Supplement
From $27

10 clinically studied strains

Delayed-release capsules

9 Enzyme-blend

150 mg of probiotics

Shelf-stable

No fillers or colors


Other brand’s supplement
Generic Health Suplement
Over $40

2–3 generic strains

Regular capsules

None

Often missing

Not always

Often fillers
Further Questions?
What makes ZBIOME different from other probiotics?
ZBIOME is formulated with clinically studied strains designed to support gut health, digestion, and overall wellness. Our unique blend ensures optimal absorption and effectiveness, helping you feel your best every day.
How should I take ZBIOME for best results?
For maximum benefits, take one capsule daily with water, preferably with a meal. Consistency is key—regular use helps maintain a balanced gut microbiome.
Is ZBIOME suitable for all dietary preferences?
Yes! ZBIOME is vegan, gluten-free, and non-GMO, making it a great choice for various dietary needs. We prioritize clean ingredients to ensure quality and effectiveness.
How long does it take to see results with ZBIOME?
While individual experiences vary, many users notice improvements in digestion and overall well-being within 2-4 weeks of consistent use. Long-term benefits continue with regular supplementation.